NBDE Part 1 – Syllabus and Questions Distribution

NBDE part 1 is an examination to get into universities in USA for DDS. NBDE Part – I consists of a total of 400 questions which are divided as follows:

NBDE part 1 syllabus and question grading

400 questions:

  • 320 questions – 80% – General discipline based questions
  • 80 questions – 20% – Ethical based questions – representing a patient scenario

Based on the previous years papers, each topic has been allotted a specific number of questions which have been mentioned below:

ANATOMIC SCIENCES – 100 questions

Gross Anatomy  – 49 questions

  • Head
  • Oral cavity
  • Extraoral structures
  • Osteology
  • TMJ and muscles of mastication
  • Neck
  • Axilla, shoulders, and upper extremities
  • Thoracic cavity
  • Abdominopelvic cavity
  • Central nervous system & neuroanatomy
  • Bone Muscles
  • Fascia Nerves (peripheral and autonomic)
  • Arteries, veins, and lymphatics Spaces and cavities
  • Joints and ligaments Endocrines and exocrines

Histology – 23 questions

  • Ultrastructure
  • Basic tissues
  • Bone, cartilage, and joints
  • Lymphatic and circulatory systems
  • Endocrine system
  • Respiratory system
  • Gastrointestinal system
  • Genitourinary system
  • Integument

Oral Histology – 16 questions

  • Tooth and supporting tissues
  • Soft oral tissues
  • Temporomandibular joint

Developmental Biology – 11 questions

  • Osteogenesis
  • Tooth development, eruption, and movement
  • Facial and brachial arch development
  • General embryology

Professional Ethics/Patient Management – 1 question

Bio Chemistry and Physiology – 100 Questions

Biological Compounds – 10 questions

  • Sugars and carbohydrates
  • Amino acids and proteins
  • Lipids
  • Nucleic acids and metabolism
  • Nutrients and minerals
  • Intradisciplinary and clinical/cross correlation

Metabolism – 17 questions

  • Bioenergetics
  • Enzymology
  • Catabolism
  • Anabolism
  • Urea cycle
  • Regulation
  • Intradisciplinary and clinical/cross correlation

Molecular and Cellular Biology – 9 questions

  • DNA/RNA and protein synthesis
  • Genetic engineering
  • Cell cycle
  • Intradisciplinary and clinical/cross correlation

Connective Tissues – 8 questions

  • Soft tissue
  • Hard tissue/calcification
  • Intradisciplinary and clinical/cross correlation

Membranes – 4 questions

  • Structure
  • Function
  • Intradisciplinary and clinical/cross correlation

Nervous System – 6 questions

  • General properties
  • Central nervous system
  • Autonomic nervous system
  • Somatic nervous system
  • Intradisciplinary and clinical/cross correlation

Muscle – 6 questions

  • Skeletal
  • Smooth
  • Cardiac
  • Intradisciplinary and clinical/cross correlation

Circulation – 9 questions

  • Fluid content and dynamics
  • Coagulation
  • Cardiodynamics and electrophysiology
  • Regulatory mechanisms
  • Intradisciplinary and clinical/cross correlation

Respiration – 6 questions

  • Mechanical aspects
  • Gas exchange and transport
  • Regulation
  • Intradisciplinary and clinical/cross correlation

Renal – 8 questions

  • Functional anatomy
  • Blood flow and filtration
  • Reabsorption and secretion
  • Regulation
  • Acid-base balance
  • Intradisciplinary and clinical/cross correlation

Oral Physiology – 3 questions

  • Taste
  • Mastication (with reflexes)
  • Swallowing

Digestion  – 5 questions

  • Neuromuscular
  • Secretions
  • Absorption
  • Regulation
  • Intradisciplinary and clinical/cross correlation

Endocrines  – 8 questions

  • Pituitary/hypothalamus
  • Reproduction
  • Signaling systems
  • Pancreas/parathyroid
  • Adrenal/thyroid
  • Intradisciplinary and clinical/cross correlation

Professional Ethics/Patient Management – 1 question

Microbiology and Pathology – 100 questions

General Microbiology – 20 questions

  • Microbial biochemistry and physiology
  • Microbial cytology
  • Microbial variations and genetics
  • Sterilization and disinfection
  • Biology of microorganisms
  • Bacteria
  • Viruses
  • Fungi
  • Antibiotics and chemotherapy
  • Oral ecology and epidemiology

Reactions of Tissue to Injury  – 10 questions

  • Inflammation and repair
  • Physical and chemical injury
  • Hemodynamic disorders

Immunology and Immunopathology – 13 questions

  • Host defense mechanisms
  • Hypersensitivity
  • Immune system

Microbiology, Immunology, and Pathology of Special Infectious Diseases – 22 questions

  • Bacterial
  • Viral
  • Fungal
  • Chlamydial and rickettsial

Systemic Pathology  – 22 questions

  • Cardiovascular
  • Respiratory
  • Gastrointestinal and hepatobiliary
  • Genitourinary
  • Blood-lymphatic
  • Endocrine
  • Musculoskeletal
  • Genetic diseases
  • Nervous system

Growth Disturbances  – 12 questions

  • Non-neoplastic
  • Neoplasms–etiology, epidemiology, & biology
  • Specific neoplasms

Professional Ethics/Patient Management  – 1 question

Dental Anatomy and Occlusion  – 100 Questions

Tooth Morphology – 43 questions

  • Primary
  • Permanent
  • Incisors
  • Canines
  • Premolars
  • Molars

Pulp Cavity Morphology  – 5 questions

Calcification and Eruption  – 6 questions

Principles of Occlusion and Function  – 37 questions

  • Functional anatomy
  • Interarch (static and movement)
  • Anterior teeth
  • Posterior teeth
  • Intra-arch
  • Masticatory physiology and biomechanics
  • Temporomandibular joint
  • Muscles and ligaments
  • Determinants of occlusion

Clinical Considerations—Tooth Morphology and Anomalies – 8 questions

Professional Ethics/Patient Management – 1 question

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