Syndromes related to Skin Diseases

Syndromes related to Skin Diseases: There are many causes of skin diseases which usually appear as a sign and symptom for an underlying disease and in some cases as an allergic reaction as well. In humans skin surface covers most of the body and many types of conditions and diseases are associated with skin disease and a condition or symptom. Out of the many causes of skin diseases, some syndromes have skin diseases as a symptom so let us see what are the various skin diseases related to syndromes.

Steven Johnson Syndrome:

  • Severe bullous form of Erythema multiforme which is a type IV hypersensitivity reaction with typical Target Lesions or Iris Lesions having mucous membrane involvement.
  • Erythema Multiforme involves skin, eyes, Oral Cavity and genitalia.
  • Hundreds of skin lesions erupt in a 24 hour period starting with back of hands and top of feet and spreading along the extremities spreading towards the trunk. The skin lesions are usually associated with itch and burning sensation.

Crest Syndrome:

It is a subtype of Scleroderma which in other words means hardened skin. The most common location for the skin disease in Crest Syndrome in the extremities is arms and legs occasionally the hardened skin appearance is seen in face and throat region as well. The other conditions associated with the syndrome are:

  • Raynauds phenomenon
  • Esophageal dysfunction
  • Sclerodactyly
  • Telangiectasia

Ehler Danlos Syndrome:

It is a connective tissue disorder with the skin showing symptoms of increased elasticity and velvety skin, fragile skin, skin that bruises easily, redundant skin folds on the eyes. The other symptoms included the following:

  • Hyperextension of joints
  • Hyper mobility of TMJ (Rubberman)
  • Vascular symptoms include fragile blood vessels, thin skin, transparent skin collapsed lung, heart valve problems etc.

Goltz Gorlin Syndrome:

  • Multi papillomas
  • Atrophy of skin
  • Polydactyly
  • Sunken eye
  • Sparse hair

Grinspan’s syndrome:

  • Characterized by triad of Lichen planus
  • Vascular Hypertension
  • Diabetes Mellitus

The other signs and symptoms of various Syndromes have been listed out to help in identifying the particular skin disease and the associated Syndrome.

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