Syndromes related to Salivary gland tumors, Cysts and Tumors of Odontogenic Origin
The list of syndromes related to the Salivary Gland tumors and the Odontogenic tumors of the oral cavity is very limited as there are not many syndromes related to these conditions. As i am sorting out the essential syndromes which are important to Dentists, we are left with 2 of the main Syndromes related to these specific conditions.
Syndromes related to Salivary Gland tumors:
Salivary Gland tumors are mostly benign accounting to almost 65% of the total and majority of those being hemangiomas. Minor Salivary gland tumors account to only 2-5% of the head and neck tumors which are benign and 2-4% of the head and neck cancers. There are no Syndromes which are known to be related to tumors but the below mentioned Syndrome is known to decrease the salivary production leading to Xerostomia.
syndromes related to odontogenic tumors of the oral cavity
Sjogren’s Syndrome:
- Xerostomia
- Keratoconjunctivitis
- Rheumatoid Arthritis
Syndromes related to Cysts and Tumors of Odontogenic Origin: Odontogenic tumors are the result of the Odontogenic cells or the cells or tissues which result in the formation of teeth, each part of the tooth is developed in specific periods of time involving both the deciduous teeth and the permanent teeth. There are many types of cells involved in this process such as ectomesenchymal cells along with the cells in the enamel organ and dental lamina are seen in the Cap stage. As the Bell stage is reached the dental organ contains cells called as stellate reticulum which are star shaped.
Gorlin Goltz Syndrome or Jaw Cyst Basal nevus – Bifid Rib Syndrome:
- Multiple Odontogenic Keratocysts
- Basal cell carcinoma
- Bifid Rib
- Neurologic, Ophthalmic and sexual abnormalities
There are other cells called the Outer Enamel Epithelium or OEE which are Cubodial in shape and seen on the periphery of the dental organ. While the columnar cells of the enamel organ adjacent to the enamel papilla as called as the Inner enamel Epithelium. Any Neoplasm of any of these cells can lead to Odontogenic Cysts and Tumors.
About The Author
Varun Pandula
I am Varun, a Dentist from Hyderabad, India trying my bit to help everyone understand Dental problems and treatments and to make Dental Education simplified for Dental Students and Dental fraternity. If you have any doubts feel free to contact me or comment in the post, thanks for visiting.
I had surgical removal of odontogenic cysts 3 times in my twenties and thirties and at approximately 6 year intervals throughout those years. I have been diagnosed with sjogrens syndrome by NIH in my sixties. I’m now 63 years old. This is the first dianeI’ve known of a relationship between these two medical issues. I am shocked.